PhD Opportunity in Bacteriophage Biology & Iron Metabolism
A cutting-edge PhD opportunity at the University of Leicester, UK, is now open for candidates interested in uncovering the fascinating relationship between iron metabolism and bacteriophage infection dynamics.
About the Project
Iron is essential for nearly all living organisms, playing a central role in respiration, DNA synthesis, and cellular metabolism. However, despite its abundance, biologically available iron is often limited. To overcome this challenge, bacteria have evolved sophisticated iron-acquisition mechanisms, including:
- Siderophore production for ferric iron capture in oxygen-rich environments
- Ferrous iron transport systems in low-oxygen or reducing environments
Recent discoveries suggest that phages may also interact with iron metabolism. Researchers have identified conserved iron-binding motifs in phage tail fibres, and studies have demonstrated direct iron binding to phage tail structures. These findings point toward a previously underexplored connection between iron availability and phage biology.
This project aims to investigate whether bacteriophages:
- Exploit iron-binding mechanisms to enhance infection efficiency
- Sequester environmental iron through conserved binding motifs
- Influence bacterial iron metabolism and physiology
Qualifications & Skills Required
- Have hands-on experience in microbiology involving bacteria and bacteriophages
- Be highly motivated, organized, and research-driven
- Demonstrate strong English communication skills
- Master’s degree (300 ECTS credits): Candidates with backgrounds in microbiology, molecular biology, bacteriophage research, microbial genetics, or related fields are encouraged to apply.
How to Apply
contact: Dr. C.W.J.
Email: cwj2@leicester.ac.uk
For more phage-related research and job opportunities, check here
This job post was originally curated by www.thephage.xyz/jobs
