Research Associate Position in Phage Manufacturing
An exciting Research Associate opportunity is open to develop new bacteriophage-based therapeutics for the treatment of antibiotic-resistant infections at Loughborough University. The work involves manufacturing and purification of bacteriophages using scalable manufacturing platforms, using bioreactors and downstream purification using membrane and chromatography process technologies.
In this project, the selected candidate will conduct extensive testing of phage nebulization and assess dose delivery in an in vitro lung-simulator model to develop phage therapeutics for infections in cystic fibrosis patients. The candidate project will also work with a commercial industrial partner. The project is led by Professor Danish J Malik.
Key Responsibilities
- Development of phage bioprocessing and test nebulization of phage formulations using a next generation impactor and breathing simulator model.
- Experimental work on the production of bacteriophage therapeutics including their purification and enumeration.
- To implement SOPs for phage manufacture and nebulization testing.
- To formulate and implement detailed plans for the project.
- Present outcomes to the investigators and sponsors.
- To assist in the development of research proposals and grant applications for follow-on project funding.
Qualifications and Skills Required
- Experience in microbiology techniques and working in a microbiology lab
- Aseptic technique and handling of microorganisms at BSL2
- Honours degree in a Science or Engineering subject or a PhD in a Science or Engineering subjects.
- Knowledge of upstream bioprocesses and culturing microbial systems
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