{"id":9242,"date":"2026-04-30T15:59:01","date_gmt":"2026-04-30T15:59:01","guid":{"rendered":"https:\/\/thephage.xyz\/jobs\/?post_type=job&#038;p=9242"},"modified":"2026-04-30T15:59:07","modified_gmt":"2026-04-30T15:59:07","slug":"phd-position-in-phage-biology-and-antimicrobial-research","status":"publish","type":"job","link":"https:\/\/thephage.xyz\/jobs\/jobs\/phd-position-in-phage-biology-and-antimicrobial-research\/","title":{"rendered":"PhD Position in Phage Biology and Antimicrobial Research"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The Institute of Biochemistry and Biophysics, Polish Academy of Sciences, invites applications for a full-time PhD position in the field of microbiology, bacteriophage biology, and antimicrobial research. This position is based in Warsaw. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project centers on <em>Staphylococcus aureus<\/em>, a major human pathogen responsible for infections ranging from mild skin conditions to severe diseases such as pneumonia and sepsis. The increasing prevalence of antibiotic-resistant strains, including MRSA, has created a critical need for alternative therapies. This PhD will investigate lytic bacteriophages from the Kayvirus genus, known for their strong activity against <em>S. aureus<\/em>. These phages encode many proteins, many of which remain uncharacterized.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Recent discoveries suggest that these phages produce novel secreted peptides during infection. These molecules may play key roles in:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Regulating phage infection cycles<\/li>\n\n\n\n<li>Influencing bacterial virulence<\/li>\n\n\n\n<li>Modulating host\u2013phage interactions<\/li>\n\n\n\n<li>Enhancing phage therapy effectiveness<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Research Objectives<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The project is structured around three main objectives:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1. <strong>Mechanisms of Peptide Maturation and Secretion<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Identify signal peptides and processing pathways<\/li>\n\n\n\n<li>Determine involvement of host vs. phage enzymes<\/li>\n\n\n\n<li>Validate mechanisms using molecular and genetic tools<\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-align-left wp-block-paragraph\"><strong>2. Functional Characterization of Phage Peptides<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Structural and computational analysis<\/li>\n\n\n\n<li>RNA-seq to study gene expression patterns<\/li>\n\n\n\n<li>Experimental assays to evaluate effects on bacterial physiology<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3. In Vivo Infection Studies<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Use <em>Caenorhabditis elegans<\/em> as an infection model<\/li>\n\n\n\n<li>Study the impact of phage peptides on virulence and infection outcomes<\/li>\n\n\n\n<li>Assess implications for phage-based therapies<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Qualifications &amp; Skills Required<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Applicants should:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Hold a Master\u2019s degree in biological sciences or a related field<\/li>\n\n\n\n<li>Have laboratory experience in microbiology or molecular biology<\/li>\n\n\n\n<li>Demonstrate strong motivation for research<\/li>\n\n\n\n<li>Possess excellent English communication skills<\/li>\n\n\n\n<li>Experience with protein work, microscopy, or related techniques is advantageous.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>For more phage-related research opportunities, check <a href=\"https:\/\/thephage.xyz\/jobs\" target=\"_blank\" rel=\"noopener\" title=\"here \">here <\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This job post was originally curated by <a href=\"https:\/\/thephage.xyz\/jobs\">www.thephage.xyz\/jobs<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Institute of Biochemistry and Biophysics, Polish Academy of Sciences, invites applications for a full-time PhD position in the field of microbiology, bacteriophage biology, and antimicrobial research. This position is based in Warsaw. The project centers on Staphylococcus aureus, a major human pathogen responsible for infections ranging from mild skin conditions to severe diseases such [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":9243,"template":"","job_type":[436],"job_discipline":[477,485],"job_location":[433],"class_list":["post-9242","job","type-job","status-publish","has-post-thumbnail","hentry","job_type-phd","job_discipline-microbiology","job_discipline-molecular-biology","job_location-poland"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.0 - aioseo.com -->\n\t<meta name=\"description\" content=\"Apply for a PhD in bacteriophage biology and Staphylococcus aureus research at the Institute of Biochemistry and Biophysics, Polish Academy of Sciences\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"The phage jobs\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/thephage.xyz\/jobs\/jobs\/phd-position-in-phage-biology-and-antimicrobial-research\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 4.9.0\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"The phage jobs - 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