Advance your understanding of microbial co-evolution and find resources on phage-host-enzyme associations, while simultaneously identifying promising candidates for phage-derived antimicrobials. The PhD candidate will gain expertise in Large-scale metagenomic assembly and genome recovery, comparative genomics and molecular evolution, Machine-learning-based protein prediction, Data integration, bioinformatics and phylogenetics. This project is offered as part of the Centre […]
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Posted
December 6, 2025
This PhD project will investigate the molecular and physiological principles of prophage interactions and their role in horizontal gene transfer and antimicrobial-resistance (AMR) dissemination. The study will be based on clinically derived S. aureus isolates that naturally harbour multiple prophages. The study will be analysing different combinations of responses to environmental and stress cues and […]
Work on understanding microbial dynamics that are important for ecological processes. Understand how the RNA phages interact with DNA phages in this PhD at the University of Southampton. Also, enhance the ecological role of RNA phages in shaping microbial community function. The PhD student will be affiliated with research groups led by Dr. Nikolic, Dr. […]
Posted
December 5, 2025
Recurrent urinary tract infections(UTIs) impair armed personnel performance, especially in women employed in UK Armed Forces. This research will use a cutting-edge lab-on-a-chip system that replicates in the human urinary tract environment. This innovative research enables realistic infection modelling and rapid testing of phage treatments under controlled conditions. By combining microbiology, bioengineering, and advanced imaging, the […]
In partnership with Biophoundry, the PhD candidate will train ML models to identify highly conserved regions on the bacterial surface. Using AI-based protein design methods, the candidate will design novel Receptor Binding Domains (RBDs) for the phage tail fibre, which will be assembled using Biophoundry’s proprietary “Trinity” technology. This will be used to generate synthetic […]
This PhD program aims to help the candidate characterize uncharted biodiversity of phages through various investigations, which include establishing a ‘natural classification’ for the phages sequenced, known as Operational Taxonomic Units (OTUs). This will be achieved by calculating pairwise genetic distances between all available phage genomes using alignment-free algorithms. The resulting network will then be […]
Posted
December 3, 2025
In this PhD, train ML models to identify highly conserved regions on the bacterial surface. He/She will design novel Receptor Binding Domains (RBDs) for the phage tail fibre, which will be assembled using Biophoundry’s proprietary “Trinity” technology for experimental validation. The computational-experimental cycle will develop effective antibacterial therapies by generating synthetic phages with a broad […]
Use predictive and generative models to decode phage genome architecture and understand how and which gene modules combine, exchange, and optimise to create functional phage genomes. Apply deep learning to understand the design principles governing phage genome organization. This PhD project at the University of BATH will focus on phage systems. Expertise and datasets from […]
Explore archaeal viruses like HHTV1 and uncover novel mechanisms. Work on understanding the assembly and infection mechanisms of archaeal viruses, which represent a major fraction of the “viral dark matter”. The viral dark matter is the vast pool of viral sequences detected in environmental samples that cannot be linked to known viruses. The supervisory team […]
Posted
December 2, 2025
Assist the AquaPhage research team as a Research Assistant to work on metagenomic analysis, isolation and propagation of cyanobacteria and their bacteriophages, and testing for cyanotoxins. The AquaPhage research team under the Department of Agriculture, Environment and Rural Affairs (DAERA) will work as part of Small Business Research Initiative (SBRI) aimed at tackling the growth of […]