Propagate and titrate various viruses (including human coronaviruses 229E and OC-43) in cell cultures and embryonated chicken eggs. Determine the efficacy of multiple disinfectants against animal and human viruses. Perform RNA extraction and RT-PCR. Prepare samples for next-generation sequencing (NGS) and analysis of NGS data. Assist in projects involving bacteria and phages. Candidates should have […]
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Bordenstein Laboratory, located at Penn State’s One Health Microbiome Center and Departments of Biology and Entomology, seeks a Research Technologist, a Life Sciences graduate, to support research on host-microbe symbioses in the reproductive tract. This work is focused on a bacterial endosymbiont (Wolbachia), phage (phage WO), and insect hosts (Drosophila flies and Aedes mosquitoes). The role will include insect […]
Single-domain antibodies, also known as nanobodies or VHHs, act as a Trojan horse for targeted brain delivery. In this position, explore the vast potential of VHHs in effectively transporting diverse molecules, ranging from proteins to nucleic acids and nanoparticles, across the blood-CSF barrier, offering promising solutions for various neurological disorders. The post-doctorate will become an […]
Work as a Research Scientist on the MRC-funded project “Mechanism of multiple drug resistance and genetic evolution of prevalent Salmonella serotypes derived from animals”, and investigate diverse Salmonella serovars across the food chain and the mechanisms of resistance development to bacteriophages and antibiotics. The ideal candidate will hold a PhD in Microbiology, Biotechnology, Bioscience Engineering, […]
The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Research Assistant in Prof. CHEN Lin’s team. The Research Assistant will play a significant role in the development and application of innovative bacteriophage-based strategies to combat multi-drug-resistant (MDR) pathogen infections. The research will focus on either the molecular engineering of […]
AbbVie is looking for a Sr. Scientist with a molecular biology and microbiology background to join their peptide display hit generation team. This role is responsible for leading and managing multiple technology development projects related to phage display of peptides for therapeutic discovery, including the generation of phage-display peptide libraries, screening against therapeutic targets, and […]
Focus on using cutting-edge science to unlock new approaches to treat people suffering from diseases with poor treatment options. Accelerate molecule discovery by building highly optimized foundational platforms, streamlining lab operations through advanced technologies, and investing in novel technologies and capabilities. Lilly Small Molecule Discovery is seeking a pioneering Mammalian Display Scientist to build and optimize a mammalian cell […]
Study how bacteria protect themselves from the phages that infect them and the countermeasures that phages use to evade these bacterial immune systems. The postdoc will investigate regulatory mechanisms of anti-phage systems. The postdoc will express and purify recombinant proteins for structural determination and biophysical characterization. The postdoc will also use molecular biology to validate […]
Lytic phages infect and kill bacterial cells to release new virions, and temperate phages can either follow the lytic pathway or enter a dormant state by integrating into the bacterial genome as a prophage. The dormant prophage may be at risk if the host is infected by a lytic phage, which would destroy both the […]
With expertise in cutting-edge proprietary technologies, Evercrisp is focused on tackling genetically validated, “difficult-to-drug” targets, particularly in areas of high unmet need where genetic medicines can create transformative outcomes. Seeking a highly motivated and ambitious protein engineer with a strong background in display technologies and molecular biology to advance miniprotein discovery projects. Roles and Responsibilities […]